Dr Gerhäuser will talk about the impact of soy isoflavones on the epigenome in breast cancer prevention during Malta Polyphenols World Congres 2015
In Malta on June 3-5, during Polyphenols World Congres 2015, Dr Gerhäuser will talk about the impact of soy isoflavones on the epigenome in breast cancer prevention.
"Within the past decade, polyphenols from various dietary sources have been shown to directly target enzymatic activities or modulate expression of enzymes involved in epigenetic gene regulation by influencing DNA methylation, chromatin structure or expression of non-coding (micro) RNAs. These effects might contribute to their chemopreventive potential mediated by effects on signal transduction mediated by nuclear receptors and transcription factors such as NF-kB, cell proliferation and cell cycle progression, cellular differentiation, DNA repair, apoptosis induction, cell motility, metastasis formation, and cellular senescence. So far, evidence of in vivo epigenetic activities in animal models and human pilot studies and its relevance for chemopreventive efficacy is limite."
To know more about Malta Polyphenols World Congress 2015: www.polyphenols-site.com
