Polyphenols, Satiety, and Gut Health: Bridging the Gut-Brain Connection

In our modern era, the spotlight is increasingly turning towards the remarkable properties of dietary polyphenols. A recent study led by researchers from Ningbo University, shedding light on their profound impact, underscores the pivotal role they play in enhancing satiety, regulating energy metabolism, and shaping overall metabolic health.

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Graphical Abstract: Dietary polyphenols promote the production of intermediary metabolites by the gut microbiota that regulate appetite, obesity and gut homeostasis in the host. Credits: Hongyan Liu et al., 2024.

Central to their efficacy is the relationship between dietary polyphenols and the gut microbiota. Through this symbiotic relationship, polyphenols unleash a cascade of metabolites that intricately influence appetite regulation. These metabolites, in turn, stimulate the release of satiety hormones such as peptide YY (PYY) and glucagon-like peptide 1 (GLP-1) along the gut-brain axis, orchestrating a harmonious balance between hunger and satisfaction.

But the influence of polyphenols doesn't stop there. Their prebiotic effects foster a flourishing gut microbiome, crucial for maintaining gut barrier integrity and overall homeostasis. By modulating the gut microbiota composition, polyphenols pave the way for a healthier internal ecosystem, with far-reaching implications for metabolic health.

Moreover, polyphenols emerge as potent allies in the battle against metabolic syndrome. By navigating various biochemical pathways, they help alleviate symptoms like inflammation and obesity, offering a multifaceted approach to holistic well-being.

The research also underscores the pressing need to delve deeper into the polyphenol-gut-brain axis, revealing its complexities and unlocking new avenues for health promotion. 

Join Polyphenols Applications 2024 this September in Milan to know more about polyphenols and gut microbiota. You can submit a related abstract. 

Read the full paper.Read the full paper.

Copyrights: Polyphenols Applications.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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