Beneficial Effects of Cornelian Cherry polyphenols on NO/ROS Balance in Obese Zucker Rats

Polyphenols Applications 2021 SpeakerProf. Olga Pechanova from Slovak Academy of Sciences, Slovakia will give a presentation entitled Beneficial Effects of Cornelian Cherry polyphenols on NO/ROS Balance in Obese Zucker Rats.

Prof. Pechanova will highlight about Cornelian cherries (CCs) that belong to promising anti-obesity substances. They aimed to study effects of coenzyme Q10 (CoQ10) and two varieties of CCs (Koralovij Marka and Wilde Type) on lipid profile, ROS, and nitric oxide (NO) production in obese Zucker rats. CoQ10 did not affect plasma lipid profile and NOS activity either in the heart left ventricle or aorta. On the other hand, Wilde Type decreased cholesterol and LDL levels. Koralovij Marka and Wilde Type increased NOS activity in the aorta, while not affecting the activity in the heart left ventricle. Koralovij Marka increased eNOS expression and did not affect ROS production, while Wilde Type increased SOD and decreased NADPH oxidase without affecting eNOS expressions in both tissues. In conclusion, CCs showed better beneficial effects than CoQ10 in all parameters studied.

Polyphenols Applications 2021 Congress
September 22-24, 2021 - Digital Congress
www.polyphenols-site.com

 

 

 

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