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Join the 17th World Congress on Polyphenols Applications 2024 on September 19-20, at Università degli Studi di Milano Statale, Milan, Italy.

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About Polyphenols Applications 2024

Polyphenols Applications 2024 Agenda


The 17th World Congress on Polyphenols Applications is scheduled on September 19-20, 2024, at the Università degli Studi di Milano Statale - Italy.

Local Organization of University of Milan

Sabrina Dallavalle, Andrea Pinto, Cristian Del Bo' and Daniela Martini.

Polyphenols Applications 2024 Aims

This edition focuses on offering a comprehensive agenda of the conference. Emphasizing the bridge between groundbreaking scientific research and its application to human health and practical outcomes in the field of polyphenols, the congress aims to foster a deeper understanding and actionable insights in polyphenol science.

The congress is committed to showcasing the latest developments in polyphenol research, with an emphasis on applying these findings for human health benefits and practical uses.


Preliminary Agenda

Day 1: Thursday, September 19

Keynote Address: Polyphenols Applications 2024: Scientific Advances and Future Directions
An extensive overview of the current state and future prospects of polyphenols, establishing the context for the conference's thematic discussions.

Session 1: Polyphenols in Health and Disease: Mechanistic Insights & Perspectives
This session explores the biological mechanisms by which polyphenols affect human health and their potential roles in disease prevention and treatment.

Lunch & Poster Session

Session 2Polyphenols, Microbiota & Metabolites: Recent Advances & Translation
Examines recent discoveries on how polyphenols interact with the gut microbiome and metabolites, highlighting their significance for human health.

 

 

Day 2: Friday, September 20

Session 3: Polyphenols in Food Science: Recent Advances
Discusses the latest efforts to integrate polyphenols into food, focusing on health benefits and environmental sustainability.

Lunch & Poster Session

Session 4: Future Directions in Polyphenol Applications
An exploratory session on emerging research areas, including:
• Extracellular Vesicles and Exosomes
• Polyphenols and Epigenetic: Towards Precision Health
• Impact of Polyphenols on Cellular Agriculture: Myth or Reality
• Polyphenols & Fermented Foods: Optimization
• Circadian Rhythms
• Artificial Intelligence

 

Special Highlight: From Research to Human Application
A consistent theme across all sessions is the focus on translating polyphenol research into real-world health benefits, illustrating the path from laboratory research to clinical application and dietary guidelines.

We wish to meet you all next September in Milan.

Dr. Jan Frederik Stevens updated

Prof. Jan Frederik Stevens
President of Polyphenols Applications
Oregon State University, USA

Tiffany Weir Earns Recognition at Polyphenols Applications 2023

Tiffany Weir 2

Dr. Tiffany Weir, a renowned professor from Colorado State University, USA, has been honored with the esteemed "Best Scientific Contribution" award at the Polyphenols Applications 2023 conference. This recognition comes on the back of her compelling presentation, "Polyphenol-Microbiome Interactions & Future of Nutrition".

With a position as a professor in Food Science and Human Nutrition at Colorado State University, Dr. Weir has made significant strides in the field. She spearheads a multifaceted translational research program, diligently uncovering the gut microbiota's role in bridging the connections between diet and host, aiming for enhanced cardiometabolic results.

As the coordinator of the Microbiome Network, she brings together a consortium of microbiome enthusiasts from various disciplines at Colorado State University. Dr. Weir's commitment to the field is further highlighted by her service as the Specialty Chief Editor for the Nutrition, Metabolism, and Microbiomes section of Frontiers in Microbiomes. Currently, she holds the esteemed position of Editor-in-Chief for npj Biofilms and Microbiomes.

A significant part of Dr. Weir's research is centered on deciphering the intricate relationship between our diets and the microbiome and its implications on human well-being. Recognizing that individual responses to dietary shifts can be highly varied, Dr. Weir and her team employ human-associated datasets and sophisticated bioinformatics tools. Their goal? To determine if variances in reactions to polyphenol interventions can be traced back to differences in gut microbial metabolism, which could, in turn, affect exposure to vital components.

The organizers and attendees of Polyphenols Applications 2023 extend their heartfelt congratulations to Dr. Weir, recognizing her commitment to and achievements in the realm of polyphenol research.


Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
Website | LinkedIn | Facebook

Outstanding Contribution by Dr. Charareh Pourzand at Polyphenols Applications 2023

Charareh Winner 1 Charareh Winner 2

The Polyphenols Applications 2023 committee acknowledges Dr. Charareh Pourzand from the University of Bath, UK, for her exemplary achievement in securing the Best Short Oral Presentation Award.

In her presentation titled "Hydroxycinnamic Acid Derivatives as Dual-Action Antioxidants and Iron Chelators for Shielding Skin Cells from UVA Photodamage", Dr. Pourzand provided a comprehensive overview of her research findings. Among the multiple hydroxycinnamic acid derivatives studied, trans-cinnamic acid (TCA) emerged as particularly potent in its photoprotective efficacy against UVA in skin cells. This was attributed to its pronounced capability to reduce both basal and UVA-induced increase in intracellular labile iron levels. Dr. Pourzand elaborated on the dual mechanistic role of hydroxycinnamic derivatives, with a notable emphasis on TCA, in counteracting UVA-induced damage in skin cells.

In general, Dr. Pourzand's Research on UVA photobiology specially in relation to skin photoaging has revealed that UVA component of sunlight has a dual damaging effect on skin cells. In one hand it generates harmful reactive oxygen species (ROS) and on the other hand it promotes the release of harmful free iron that acts as a catalyst to exacerbate the damaging effect of ROS, leading to irreversible skin photodamage in the form of wrinkling, sagging, etc .

Dr. Pourzand stated: "To counteract this dual effect of UVA, we are in process of identifying natural compounds based on polyphenols that can not only neutralise the UVA-induced ROS but also mop the free iron released by UVA. Since the properties and the concentration of such polyphenols can significantly change in different seasons or locations, our future research is concentrated on designing 'bio-inspired' molecules that are more stable than their natural counterparts but still maintain their dual functions. Such bifunctional compounds  can then be added as photo-protectants into sunscreen formulations for a more robust protection against UVA photodamge exerted by sunlight".    

Such advancements in the field of skin photoprotection are of immense importance, and the Polyphenols Applications 2023 team, along with the broader scientific community, recognizes and appreciates Dr. Pourzand's significant contribution.


Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
Website | LinkedIn | Facebook

Best Poster Presentation Award of Polyphenols Applications 2023

Best Poster Award 2023

The Polyphenols Applications 2023 committee extends its sincere commendation to Samuele Venturi from Università degli Studi di Milano, Italy, for his distinguished achievement in receiving the Best Poster Presentation Award.

His research, titled "Effect of a Serving of Wild Blueberry (Vaccinium Angustifolium) Drink on Vascular Function Markers in Healthy Subjects: A Randomized, Placebo-controlled, Crossover Study", contributes to the understanding of dietary polyphenols and their potential cardiovascular benefits.

Furthermore, our gratitude extends to Dr. Cristian DelBo', a prominent speaker at Polyphenols Applications 2023. As the corresponding author, Dr. DelBo' played an instrumental role in guiding and supporting this award-winning research.

This study embodies the commitment to advancing scientific knowledge within the realm of polyphenol research. The committee and the broader scientific community recognize and value the significant contributions of both researchers.


Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
Website | LinkedIn | Facebook

Polyphenols Innovation Network: Call for Projects

Polyphenols-TaskForce-Logo

Please find here more information about the "Polyphenols Innovation Network" (PIN) & its projects.

Polyphenols Innovation Network

We are delighted to announce the launch of the Polyphenols Innovation Network (PIN), a pioneering initiative designed to accelerate progress in the field of polyphenols research by fostering a collaborative and innovative environment.

Aim of the Network

Under the banner of PIN, our mission is to assemble a diverse team of multidisciplinary experts, committed to advancing the frontiers of polyphenols research, applications, and innovation.


Projects of PIN

Three pioneering projects have been earmarked for initiation under the auspices of PIN:

Project 1: Artificial Intelligence and Polyphenols

This project will utilize AI's power to delve deeper into the understanding and utilization of polyphenols, aiming to develop predictive models for identifying novel therapeutic polyphenols and optimizing their formulations. 

Learn more.

Project 2: Longevity & Polyphenols

Our focus here is on exploring the role of polyphenols in promoting longevity and preventing age-related diseases. We aim to uncover the molecular mechanisms through which polyphenols exert their beneficial effects on lifespan and healthspan.

More details.

Project 3: Space Food & Polyphenols

This project centers on creating polyphenol-enriched space food to boost astronauts' nutrition and well-being during space missions.

Learn more.


Funding of Projects

The Polyphenols Innovation Network is dedicated to securing necessary resources from public and private institutions to support these groundbreaking efforts.


How to participate?

To contribute to one of these 3 pioneering projects, Polyphenols Applications requests interested researchers and teams to submit a proposal detailing the following aspects:

  • Project Overview: Please provide a concise description of your current research or project. Include key goals, methodologies used, and any preliminary results or findings that could highlight the relevance and potential impact of your work.
  • Alignment with PIN Goals: Articulate how your work contributes to the broader objectives of PIN. This could be in terms of techniques being developed, the specific aspects your project focuses on, or the potential applications of your research.
  • Challenges and Solutions: Identify any potential hurdles or obstacles you anticipate in the course of your research. This could be technical issues, logistical constraints, or theoretical problems. Additionally, provide an outline of how you propose to tackle these challenges. This shows proactive problem-solving and can help us better understand the feasibility of your project.
  • Team Profile: Furnish an overview of your team and its expertise. Highlight the skills, qualifications, and experiences of your team members that make them well-equipped to carry out the proposed project. Include any past achievements or relevant projects that demonstrate your team’s capacity to successfully execute the research.

We invite interested researchers and teams to join PIN by submitting their project proposals to polyphenols(at)polyphenols-site.com by April 10, 2024.

Submissions should include a project overview, its alignment with PIN's goals, anticipated challenges and proposed solutions, and a team profile. Proposals will be evaluated by our Selection Committee, and successful applicants will be invited to participate in the next phase of our initiative.

 

Polyphenols Applications 2023 Posters List

LOGOS-POLYPHENOLS-UPDATED

More than 120 communicationswere presented during Polyphenols Applications 2023.  Access full posters list.

Posters 2

Polyphenols Applications 2023 Congress
September 29-29, 2023 - Malta
Website | LinkedIn | Facebook

Natural polyphenol supplements reduce dietary iron absorption in adults with iron-loading diseases

Michael ZimmermannProf. Michael Bruce Zimmermann, ETH Zurich, Switzerland, will join the Polyphenols Applications 2023 Congress and present his latest rearch about the "Natural polyphenol supplements reduce dietary iron absorption in adults with iron-loading diseases".

Dr. Zimmermann and his colleagues developed a new natural polyphenol supplement that strongly chelates iron in vitro and assessed its effect on non-heme iron absorption in patients with hereditary hemochromatosis (HH). The polyphenol supplement reduced iron absorption by ~ 40% from meals and test drinks.

Their results indicate that when taken with meals, this natural polyphenol supplement can decrease dietary iron absorption, and might thereby reduce toxicity of body iron accumulation in patients with HH.

Join us in Polyphenols Applications 2023 to learn more about Prof. Zimmermann's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Polyphenol-Microbiome Interactions & Future of Nutrition

Tiffany WeirDr. Tiffany Weir, Colorado State University USA, will join the Polyphenols Applications 2023 Congress and present her latest rearch about the interactions between polyphenols and the microbiome. 

Although consumption of dietary polyphenols is widely acknowledged as beneficial for human health, there is a high degree of variability in individual responses. Some of this variability may be due to differential processing of dietary polyphenols by the gut microbiome. Polyphenol metabolizing enzymes in the gut microbiota can influence the bioactivity and bioavailability of these compounds.

Dr. Weir and her colleagues are working to understand whether these polyphenol metabolizing enzymes are predictive of individual responses in vascular endothelial function to a dietary blueberry intervention in post-menopausal women. More broadly, understanding polyphenol metabolism in the gut will advance precision nutrition and potentially help identify complementary approaches to improve outcomes to nutrition interventions.

Dr. Weir will give a presentation titled: "Polyphenol-Microbiome Interactions & Future of Nutrition"


About Dr. Weir

Dr. Tiffany Weir is a professor of Food Science and Human Nutrition at Colorado State University. She leads an interdisciplinary translational research program focused on identifying the role of the gut microbiota in mediating diet-host interactions for improved cardiometabolic outcomes. Dr. Weir is the coordinator of the Microbiome Network, an interdisciplinary research and education consortium of microbiome scientists at Colorado State University. She also served as the Specialty Chief Editor for the Nutrition, Metabolism, and Microbiomes section of Frontiers in Microbiomes and is currently the Editor-in-Chief for npj Biofilms and Microbiomes.


Join us in Polyphenols Applications 2023 to learn more about Prof. Weir's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Polyphenols & Immunomodulation: What do we know?

Hanne FrøkiærProf. Hanne Frøkiær, University of Copenhagen, Denmarkwill join the Polyphenols Applications 2023 Congress and present her latest rearch about the "Polyphenols & Immunomodulation: What do we know?".

Join us in Polyphenols Applications 2023 to learn more about Prof. Frøkiær's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Role of Polyphenolic Caffeoylquinic Acids in the Neurological Effects of Centella asiatica

Amala Soumyanath 1Dr. Amala Soumyanath, Oregon Health & Science University, USAwill join the Polyphenols Applications 2023 Congress and present his latest rearch about the "Role of Polyphenolic Caffeoylquinic Acids in the Neurological Effects of Centella asiatica".

The traditional herbal remedy, Centella asiatica, shows remarkable effects related to cognitive function and mood in preclinical models.  Its abundant triterpene constituents are usually reported as the active compounds.

However,  studies conducted by Dr. Soumyanath and her colleagues, show that polyphenolic caffeoylquinic acid isomers also play an important role in this herb’s neurotropic effects in vitro and in vivo.

Join us in Polyphenols Applications 2023 to learn more about this topic.

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Deglycosylation of secondary plant metabolites by lactobacilli

Dr. Michael Ganzle-v1Prof. Michael Gänzle, University of Alberta, Canadawill join the Polyphenols Applications 2023 Congress and present his latest rearch about the "Deglycosylation of secondary plant metabolites by lactobacilli".

Lactobacillaceae are among the major fermentation organisms in food fermentations but their metabolic pathways for conversion of (poly)-phenolic compounds have been elucidated only in the past two decades. The first step of conversion is the hydrolysis of esters or glycosides of phenolic compounds. This study aimed to evaluate the ability of Lactobacillus crispatus FUA3540, Companilactobacillus paralimentarius FUA3121, Lacticaseibacillus paracasei FUA3413, Lactiplantibacillus plantarum TMW1.460, Levilactobacillus hammesii LP38T, Furfurilactobacillus rossiae FUA3124, and Ff. milii FUA3430T and Fructilactobacillus sanfranciscensis DSM20451T to hydrolyse glycosides of secondary plant metabolites.

The genomes of these strains encoded for 5, 20, 8, 10, 2, 1, 2 and 0 β-glucosidases or phospho‑β‑glucosidases, respectively. L. crispatus, Cp. paralimentarius, Lc. paracasei and Lp. plantarum but not Lv. hammesii, Ff. rossiae or Ff. milii hydrolysed cellobiose. The hydrolysis of amygladin, esculin, and salicin matched the hydrolysis of cellobiose. With exception of Fl. sanfranciscensis, all strains hydrolysed spiraeoside and genistin. Lp. plantarum and Cp. paralimentarius additionally hydrolysed isoquercetin.

Prof. Gänzle's data support the previous observation that many of the glycosyl hydrolases in lactobacilli are specific for glycosylated secondary plant metabolites rather than di- and oligosaccharides. Increased knowledge on their substrate specificity will facilitate the selection of fermentation organisms to secondary plant metabolites with desirable or undesirable biological activities in food fermentations.

Join us in Polyphenols Applications 2023 to learn more about Prof. Gänzle's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Sustainable sources for Polyphenols Recovery and their Application in Healthy Food

Isabella DAntuono 3Dr. Isabella D’Antuono from the Institute of Sciences of Food Production National Research Council (ISPA – CNR), Italy, will join the Polyphenols Applications 2023 Congress and present the talk entitled "Sustainable Sources for Polyphenols Recovery and their Application in Healthy Food".

Functional foods are an innovative response of food industries to consumer expectations. Their sector includes foods naturally rich in bioactive compounds or enriched in bio-ingredients stemming from unexploited sources, as a virtuous application of the circular economy concept.

Join us in Polyphenols Applications 2023 to learn more about Dr. D’Antuono's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Polyphenols in Depression & Neurodegenerative Diseases

Prof. Giulio Maria Pasinetti from PasinettiIcahn School of Medicine at Mount Sinai, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Polyphenols in Depression & Neurodegenerative Diseases".

Join us in Polyphenols Applications 2023 to learn more about Dr. Pasinetti's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

 

Book your hotel and benefit from the best rate

corinthia-palace-malta-exterior-1973-x-1315

Corinthia Palace Malta will be the conference hotel of Polyphenols Applications 2023 on September 28-29.

Hotel Booking for Attendees: Special Rate

This year's attendees will be able to benefit from a discount on their booking at the conference hotel.

Available rooms include: Deluxe double, executive double, and executive suites for sole use.

The room rate includes full breakfast and VAT. Please note that the offer is valid until July 31, with a limited number of rooms.

Book you room with a preferential rate now.

If you need more than 2 rooms, please contact the hotel directly via email, mentioning that you will attend Polyphenols Applications 2023.

More about the hotel and activities in Malta.

Registration Details

Register early and book your spot to to learn about this year's new scientific outlook on Polyphenols Applications in lovely Malta.


Polyphenols Applications Congress
September 28-29, 2023 - Malta
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Book your hotel and benefit from the best rate (2)

corinthia-palace-malta-exterior-1973-x-1315

Corinthia Palace Malta will be the conference hotel of Polyphenols Applications 2023 on September 28-29.

Hotel Booking for Attendees: Special Rate

This year's attendees will be able to benefit from a discount on their booking at the conference hotel.

Available rooms include: Deluxe double, executive double, and executive suites for sole use.

The room rate includes full breakfast and VAT. Please note that the offer is valid until July 31, with a limited number of rooms.

Book you room with a preferential rate now.

If you need more than 2 rooms, please contact the hotel directly via email, mentioning that you will attend Polyphenols Applications 2023.

More about the hotel and activities in Malta.

Registration Details

Register early and book your spot to to learn about this year's new scientific outlook on Polyphenols Applications in lovely Malta.


Polyphenols Applications Congress
September 28-29, 2023 - Malta
linked in icon-Facebook icon-removebg-preview

Plant-Derived Polyphenols as Senolytic Agents

Christopher Wiley 2 1Cellular senescence is a basic aging process that drives several age-related degenerative conditions.  Compounds that selectively eliminate senescent cells, commonly called “senolytics”, have the potential to improve multiple degenerative conditions by targeting this key age-promoting process. 

Several polyphenols have been shown to have senolytic activity, including the hops-derived chalconoid xanthohumol, presenting a new pathway by which these molecules might improve degenerative disease.  

Dr. Christopher Wiley from Tufts University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Plant-Derived Polyphenols as Senolytic Agents".


 About Dr. Wiley

Dr. Wiley is a Scientist II at the Jean Mayer USDA Human Nutrition Research Center on Aging and an Assistant Professor in the School of Medicine at Tufts University.  His laboratory studies the interactions between metabolism and cell fate decisions such as cellular senescence and cell death, primarily in the context of aging and degenerative disease.  


Join us in Polyphenols Applications 2023 to learn more about Dr. Wiley's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

 

Cranberry Polyphenols Inhibit Esophageal Cancer Through Reshapeing the Microbiome-Metabolome Axis

Laura KrestyDr. Laura Kresty from the University of Michigan, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Cranberry Polyphenols Inhibit Esophageal Cancer Through Reshapeing the Microbiome-Metabolome Axis".

Join us in Polyphenols Applications 2023 to learn more about Dr. Kresty's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Catechol-based Nanostructures in Medicine

Daniel RuizProf. Daniel Ruiz Molina from Universitat Autònoma de Barcelona, Spain, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Catechol-based Nanostructures in Medicine".

The experience and background of the team brings an important asset in the synthesis of “sticky” catechol based coatings and nanoparticles with bioadhesion properties in humid conditions. This involves: I)  Synthesis of nanoparticles/nanocapsules intended for chemo-/phototherapy with encapsulated drugs and study of the controlled release, II) novel coating for biofunctionalization, colloidal stabilization in physiological media experimental conditions and III) a patch to damaged tissue that allow for the growth of healthy cells in a very effective way that will naturally induce a faster regeneration of the tissue.

Join us in Polyphenols Applications 2023 to learn more about Prof. Ruiz's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols

Diana Roopchand 2Dr. Diana Roopchand from Rutgers University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols".

Grape polyphenols (GPs) extracted from grape pomace are rich in proanthocyanidins (PACs) compounds which are not bioavailable; however, evidence suggests their health benefits are likely mediated via the gut microbiota and/or bacterial metabolites.

Serum, fecal, and/or urine samples were collected before and after 2, 4, and 10 days of GP supplementation followed by shotgun metagenomic sequencing, mass spectrometry-based metaproteomics, and/or targeted metabolomics. Notable GP-induced bile acid changes appeared to be gender-specific and correlational analyses uncovered novel associations between gut microbes and metabolites associated with metabolic resilience.

Join us in Polyphenols Applications 2023 to learn more about Prof. Roopchand's talk. 

Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com

 

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