Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols
Dr. Diana Roopchand from Rutgers University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols".
Grape polyphenols (GPs) extracted from grape pomace are rich in proanthocyanidins (PACs) compounds which are not bioavailable; however, evidence suggests their health benefits are likely mediated via the gut microbiota and/or bacterial metabolites.
Serum, fecal, and/or urine samples were collected before and after 2, 4, and 10 days of GP supplementation followed by shotgun metagenomic sequencing, mass spectrometry-based metaproteomics, and/or targeted metabolomics. Notable GP-induced bile acid changes appeared to be gender-specific and correlational analyses uncovered novel associations between gut microbes and metabolites associated with metabolic resilience.
Join us in Polyphenols Applications 2023 to learn more about Prof. Roopchand's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
