Health-Promoting Effects of Hop-Derived Polyphenols Involve Modulation of the Gut-Liver-Brain Axis
Prof. Jan Frederik Stevens, from Oregon State University, USA, will join Polyphenols Applications 2021 in September to give a talk about "Health-Promoting Effects of Hop-Derived Polyphenols Involve Modulation of the Gut-Liver-Brain Axis".
The main idea that Prof. Stevens will discuss concerns the increasing fact that the antioxidant and anti-inflammation hypothesis for polyphenol activity offers an unsatisfactory explanation for the health-promoting effects of dietary polyphenols. He confirms that using preclinical models of metabolic syndrome combined with a multi-organ, multi-omics data generation approach, it has been found that oral treatment of mice with the hop-derived polyphenol, xanthohumol, decreases liver fat accumulation, improves glucose tolerance, and mitigates cognitive impairments via modulation of the gut microbiota, nuclear receptor signaling, and via targeting metabolism that alters bile acid composition and suppresses ceramide accumulation.
Polyphenols Applications 2021 Congress
September 22-24, 2021 - Digital Congress
www.polyphenols-site.com
