Spain Polyphenols Applications is postponed to 2021

Dear Colleagues,

 

In response to the critical situation and evolution of the COVID-19, the Organizing Committee of Polyphenols Applications 2020 decided to postpone the congress to next year.

 

We will announce the details as soon as the planning of the 2021 meeting has been completed.

 

We will keep your registration, you don’t need to do anything.  In case of cancellation, the Organizing Committee will fully refund you.
Thank you for your understanding of this exceptional situation.

 

We will keep our optimism and wish rapidly to overcome these moments.

 

All our warm regards,

 

Prof. Dr. Andreas Schieber                      
President of Polyphenols Applications 2020
University of Bonn, Germany 

 

Dietary flavonols and risk of Alzheimer dementia

13954

Objective To determine whether dietary intake of flavonols is associated with Alzheimer dementia.

Methods The study was conducted among 921 participants of the Rush Memory and Aging Project (MAP), an ongoing community-based, prospective cohort. Participants completed annual neurologic evaluations and dietary assessments using a validated food frequency questionnaire.

Results Among 921 MAP participants who initially had no dementia in the analyzed sample, 220 developed Alzheimer dementia. The mean age of the sample was 81.2 years (SD 7.2), with the majority (n = 691, 75%) being female. Participants with the highest intake of total flavonols had higher levels of education and more participation in physical and cognitive activities. In Cox proportional hazards models, dietary intakes of flavonols were inversely associated with incident Alzheimer dementia in models adjusted for age, sex, education, APOE ɛ4, and participation in cognitive and physical activities. Hazard ratios (HRs) for the fifth vs first quintiles of intake were as follows: for total flavonol, 0.52 (95% confidence interval [CI], 0.33–0.84); for kaempferol, 0.49 (95% CI, 0.31–0.77); for myricetin, 0.62 (95% CI, 0.4–0.97); and for isorhamnetin, 0.62 (95% CI, 0.39–0.98). Quercetin was not associated with Alzheimer dementia (HR, 0.69; 95% CI, 0.43–1.09).

Conclusion Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.


Authors: Thomas M. Holland, MD, Puja Agarwal, PhD, Yamin Wang, PhD, Sue E. Leurgans, PhD, David A. Bennett, MD, Sarah L. Booth, PhD, and Martha Clare Morris, ScD
Journal: Neurology® 2020;94:1-8. doi:10.1212/WNL.0000000000008981