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Extracting polyphenols: trying to get the best

PValentao 3Professor Patrícia Valentão from Universidade do Porto, Portugal will present Extracting polyphenols: trying to get the best.

According to Pr. Valentão, nature has been a prolific source of interesting compounds for many years. Polyphenols are secondary metabolites found in both terrestrial and marine organisms. They are grouped in several classes resulting from acetate and/or shikimate pathways, being recognized for having a wide array of biological properties. Nevertheless, the exploitation of many plant materials and marine organisms as sources of these compounds is still reduced, due to the lack of popularity or commercial interest. The suitable extraction procedure depends on the class of compounds and on the matrix in which they are contained. Case studies, involving different procedures to obtain bioactive natural extracts enriched in phenolic compounds from distinct classes, will be focused. Terrestrial and marine-derived extracts, containing phlorotannins, flavonoids and cinnamoyl derivatives, and their interference in SNC and gastrointestinal disorders, skin aging and fungal infections will be presented.

For more information about the congress please visit: www.polyphenols-site.com.

Systemic absorption, metabolism, and bioavailability of dietary procyanidins in pigs

HumpfProfessor Hans-Ulrich Humpf from the Institute of Food Chemistry, Westfälische Wilhelms-Universität Münster of Germany will present Systemic absorption, metabolism, and bioavailability of dietary procyanidins in pigs.

According to Pr. Humpf, procyanidins are oligomers of catechin and epicatechin and they can be found in a large number of foods including various fruits. The daily consumption is estimated to be in the range of approximately 50 mg. Procyanidins are described to exhibit beneficial health effects, however the knowledge about their absorption and meta-bolic fate is rather limited. To study the systemic absorption and metabolism of pro-cyani¬dins a kinetic study with pigs was performed as they have a gastro-intestinal tract very similar to humans. After oral application of a procyanidin extract or a single dose of pure procyanidin B4 to pigs urine and plasma samples were collected and analyzed by HPLC-MS/MS. The results clearly indicate the absorption of low molecular weight procyanidins (dimers and trimers) in the nanomolar range and their metabolism to small phenolic degradation products during the passage of the gastro-intestinal tract.

For mor information about the congress please visit: www.polyphenols-site.com.

Neuroprotective Role of Natural Polyphenols: a Look to the Potentiality of Elderberry Extracts

SpagnuoloCDr. Carmela Spagnuolo from the Institute of Food Sciences, National Research Council in Italy will talk about Neuroprotective Role of Natural Polyphenols: a Look to the Potentiality of Elderberry Extracts.

According to Dr. Spagnuolo, neurodegenerative diseases cause a progressive functional alteration of neuronal systems, resulting in a state of dementia which is considered one of the most common psychiatric disorders of the elderly. Polyphenols may behave as potential neuroprotective agents, since their ability to influence and modulate key cellular processes implicated in neurodegeneration. Several studies show the promising neuroprotective effects of herbal compounds (e.g., (-)-epigallocatechin-3-gallate, resveratrol, curcumin, quercetin and others) or extracts (e.g. tea polyphenols). Berries represent a rich source of flavonoids and among them, we showed that Sambucus nigra extract possesses elevated polyphenolic content and antioxidant capacity.

For more information about this congress please visit: www.polyphenols-site.com.

Industrial dosage forms to improve the oral bioavailability of resveratrol

Teofilo VasconcelosWe are pleased to welcome Professor Teófilo Vasconcelos from INEB-I3S of University of Porto in Portugal at the 10th World Congress on Polyphenols Applications: Porto Polyphenols 2016.
During this congress, Pr. Vasconcelos will talk about the industrial dosage forms to improve the oral bioavailability of resveratrol.

According to Pr. Vasconcelos, polyphenols are interesting compounds that present several difficulties in oral administration. The proposed presentation intends to highlight the challenges of developing pharmaceutical products containing Polyphenols. In particular, drug delivery approaches that can be used to overcome and/or potentiate the Polyphenols drug properties will be presented.

For more information about the congress please visit: www.polyphenols-site.com.

The hormetic role of redox-active polyphenols in human health and disease

Teixeira big picDr. José Teixeira from Universidade do Porto in Portugal  will talk about the hormetic role of redox-active polyphenols in human health and disease.

According to Dr Teixeira, polyphenols are well-known antioxidant molecules, which present different mechanisms at several subcellular compartments.
- Polyphenols, in its oxidized quinone form, may act as potent regulators of the cellular redox status.
- Mitochondria, the cell’s powerhouse, adapt to environmental factors by producing effectors that activate multiple pathways related to oxidative stress balance.
- Targeting mitochondria with therapeutic agents is an effective therapeutic strategy in human health and disease.
- Re-designing natural products and improving intracellular addressing can be a promising strategy to improve the cellular antioxidant status and contribute to decrease oxidative stress.

For more information about the congress please visit www.polyphenols-site.com.

Are polyphenols strong dietary agents against neurotoxicity and neurodegeneration?

Polyphenols

According a recent study published by Dr. Branca Maria Silva from the University of Beira Interior, Portugal, the polyphenols can be considered as strong dietary agents against against neurotoxicity and neurodegeneration?

In this study which will be presented during Porto Polyphenols World Congress 2016, Dr Silva discussed whether polyphenols obtained from diet or food supplements are an effective strategy to prevent or treat neurodegeneration. She also discussed the safety, mechanisms of action, and the current and future relevance of polyphenols in clinical treatment of neurodegenerative diseases. 

For more information about this study, don't hesitate to register on www.polyphenols-site.com

 

ELKEN was awarded for the Best Innovative Ingredient 2015

 

During Malta Polyphenols 2015, Dr Pierluiggi Vitti, from Hospital St James, Malta presented a talk about " Elken Fermented Spirulina for Anti-Inflammation and Liver Protection "
 
The scientific committee awarded Elken Innovation Centre, AK Tan for Elken fermented spirulina as the Best Innovative Ingredient 2015.
 

On behalf of Malta Polyphenols 2015

http://www.polyphenols-site.com/

Pr Richard Maroun from the Saint-Joseph University of Beirut was awarded for his scientific contribution during Malta Polyphenols 2015

Pr Maroun V3During the 9th World Congress on Polyphenols Applications held in Malta between June 3 and 5, 2015 Pr. Maroun, a member of the steering committee of the congress was awarded for his scientific contribution. 

His presentation focusef on "Optimization of Polyphenols Extraction from Wine Shoots & Grape Pomace".

On behalf of ISANH and Polyphenols Committee, we congratulate Pr. Maroun for this award.

 

Malta Polyphenols Team
www.polyphenols-site.com

 

 

 

Professor Elke Richling will talk about investigating the biological effects of Anthocyanins from Fruits

MaltaPolyphenolsPr. Elke Richling, professor in Kaiserslautern university in Germany, will talk about the investigations of the biological effects of Anthocyanins during Malta Polyphenols World Congress on June 3-5, 2015, in St Julian's, Malta.

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The Scientific Committee is pleased to announce that Pr Rufian Henares will present the Antioxidants Activity of Polyphenols in Food & Human Plasma

Dr RufianPr Rufian Henares will describe the Antioxidants Activity of Polyphenols in Food & Human Plasma: Towards a ISANH Standard, during Malta Polyphenols World Congress 2015 held on June 3-5, 2015, in St Julian's, Malta.

"The assessment of antioxidant capacity of those polyphenols or metabolites present in foods and plasma is a hot topic due to the direct relationship with human health and different analytical issues. The present lecture will show current approaches to develop a standardized protocol to measure the antioxidant activity of digested foodstuffs as well as plasma samples. The solubilization constrains of polyphenols during food extraction will be discussed as well as the different analytical approaches for in vitro measurement of antioxidant capacity with relevant physiological radicals."

To know more about the Malta Polyphenols World Congress 2015, please click here.

Malta Polyphenols Team
www.polyphenols-site.com

Pr. Chrubasik-Hausmann will present Clinical Importance of Polyphenol Analyses in Functional Food during Malta Polyphenols World Congress 2015

Malta Polyphenols- Pr.Chrubasik

Pr. Sigrun Chrubasik-Hausmann, specialist in general practice, will talk about clinical importance of Polyphenol Analyses in Functional Food during Malta Polyphenols World Congress on June 3-5, 2015, in St Julian's, Malta.

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A special session, chaired by Pr Reinhold Carle, and dedicated to Natural Pigments & Colorants 2015: Food & Beverages Applications is organized during Malta Polyphenols World Congress


Pr. Reinhold CarleThe Scientific Committee of Malta Polyphenols organizes a special session dedicated to Natural Pigments & Colorants: Food & Beverage Applications.

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Pr Erdogan Orhan from the Gazi University will present Polyphenol Derivatives as Potent Tyrosinase Inhibitors during Malta Polyphenols World Congress 2015

PrOrhanDuring the Malta Polyphenols World Congress 2015, held between June 3-5, Pr. Erdogan Orhan from the Gazi University will present the potent action of Polyphenol Derivatives as Tyrosinase Inhibitors.

"Polyphenols are an abundant chemical class of secondary metabolites in the plant kingdom with desired pharmacological activities for human health. The main function of tyrosinase (TYR, EC 1.14.18.1), a member of polyphenol oxidases (PPOs) having dinuclear copper centers, is known to catalyze browning reactions in vegetables and fruits due to the oxidation and dehydrogenation reactions of polyphenols and, therefore, inhibition of TYR is critical in food industry. Besides, inhibitors of TYR are widely employed in skin-whitening (bleaching) products in cosmetics industry and for the treatment of melanoma. More recently, TYR inhibitors have been searched for the possible treatment of Parkinson’s disease. In this talk, polyphenol type of TYR inhibitors will be discussed."

To know more about Malta Polyphenols World Congress 2015, please click here.

Dr Gerhäuser will talk about the impact of soy isoflavones on the epigenome in breast cancer prevention during Malta Polyphenols World Congres 2015

Dr Gerhauser 2In Malta on June 3-5, during Polyphenols World Congres 2015, Dr Gerhäuser will talk about the impact of soy isoflavones on the epigenome in breast cancer prevention.

"Within the past decade, polyphenols from various dietary sources have been shown to directly target enzymatic activities or modulate expression of enzymes involved in epigenetic gene regulation by influencing DNA methylation, chromatin structure or expression of non-coding (micro) RNAs. These effects might contribute to their chemopreventive potential mediated by effects on signal transduction mediated by nuclear receptors and transcription factors such as NF-kB, cell proliferation and cell cycle progression, cellular differentiation, DNA repair, apoptosis induction, cell motility, metastasis formation, and cellular senescence. So far, evidence of in vivo epigenetic activities in animal models and human pilot studies and its relevance for chemopreventive efficacy is limite."

To know more about Malta Polyphenols World Congress 2015: www.polyphenols-site.com

Pr Vanden Berghe will give a talk on the role of dietary lifestyle choices in the healthy aging mechanisms during Malta Polyphenols World Congress 2015

Pr Vanden Berghe Wim2Pr Vanden Berghe will give a talk during the Malta Polyphenols World Congress 2015 held between June 3-5.

"Nowadays, epigenetic mechanisms involving DNA methylation, histone modification and microRNA regulation may provide an explanation for the strong interindividual variation in disease risk factors underlying CVD. Dietary lifestyle may strongly affect CVD risk by metabolic (re)programming of our epigenome in utero, after birth or during life. In contrast to genetic mutations, the plasticity of CVD related epigenetic changes makes them attractive candidates for nutritional prevention. The involvement of epigenetic alterations in atherosclerosis will be discussed in relation to the epigenetic impact of a cocoa flavanol diet intervention in the context of personalized nutrition and cardioprotection."

The presentation of Pr Vanden Berghe will discuss the if epigenetics is the key to a personalized nutrition and how to transform inflammaging to healthy aging by dietary lifestyle.

 

To know more about Malta Polyphenols World Congress 2015, click here.

 

 

 

 

Pr Meireles will present different methods of Polyphenols Extraction at the workshop "Utilization of By-products of Food Processing" during the 9th World Congress on Polyphenols Applications

Pr Meireles 2During the Workshop at the Malta Polyphenols World Congress 2015 held on June 3-5, Pr Meireles will present Extraction of Polyphenols From Food By-Products Using Green Solvents: Supercritical Carbon Dioxide, Pressurized Ethanol, Ethanol And Water.

 

"In this talk, a discussion of extraction of polyphenols from food by-products will,be presented. The presentation will be focused on obtaining polyphenols using supercritical fluid extraction using water (SFEW)1 and ethanol (SFE-EtOH)2 as cosolvents, the use of pressurized ethanol extraction and the use of lowpressure ethanol extraction. The use of polyphenols using supercritical fluid extraction with ethanol as cosolvent will be focused in the use of residue of jabuticaba (Myrciaria cauliflora) and grape bagasse from the Peruvian Pisco industry. "

 

To know more about the workshop on Utilization of By-products of Food Processing and the Malta Polyphenols World Congress 2015, click here.

Pr Dimitrov will give a talk about Polyphenols from Berry By-Products during the workshop of Malta Polyphenols Congress 2015

dr Krasimir DimitrosDuring the Workshop Utilization of by-Products of Food Processing, Pr. Dimitrov will give a talk about Polyphenols from Berry By-Products, On June 3.

"Among all common fruits and vegetables, berries, especially those with dark blue or red colors, have the highest antioxidants capacities.

After Juice extraction, many phenolic compounds and especially antocyanins, are still present in the solid wastes abd could be valorized by suitable extraction process. In this talk a review of berries wastes and antioxidant phenolics in such by-products, classical and alternative extraction techniques for their recovery and techniques for the enrichement of the obtained extracts, their drying and encapsulation, as well as some potential uses of these extracts as natural ingredients (antioxidants, colorants, etc.) in food, cosmetic and pharmaceutical industries will be presented".

 

To know more about Malta Polyphenols World Congress 2015, please click here.



During the Symposium of Malta Polyphenols World Congress 2015, Mrs Gras will give a talk about separation for analysis of Anthocyanins by two different methods from different black carrot

DrGras2Mrs. Gras from the Hohenheim University, will give a talk on June 3 during the symposium on Natural Pigments & Colorants 2015, about Comparison of HPLC and UPLC separation for analysis of anthocyanins from different black carrot varieties (Daucus Carota ssp. Sativus var. Atrorubens Alef).

"Anthocyanins from black carrot (Daucus carota ssp. sativus var. atrorubens Alef.) are natural phenolic pigments widely used for coloring beverages, fruit preparations and confectionary, resulting in a bright red shade at low pH values. They are extraordinarily stable against light and heat exposition due to a high proportion of acylated anthocyanins, which are stabilized via intramolecular co-pigmentation. In the present talk, an ultrasound assisted anthocyanin extraction, their identification and quantitation on a common HPLC-PDA equipped with a C18 core-shell column and modern UPLC-PDA system using a C18 sub-2 µm column were applied and validated. Applying an optimized UPLC separation, differences in the anthocyanin levels in different black carrot varieties will be presented."

 

To know more about Malta Polyphenols World Congress 2015, please click here.

During Malta Polyphenols World Congress 2015, Dr Buchweitz will talk about Stabilisation of anthocyanins and anthocyanin–metal chelates with pectins for their application as red and blue food colourants

Dr Buchweitz

Dr. Buchweitz will give a talk during Polyphenols World Congres 2015 held in Malta on June 3-5, about the stabilisation of metal chelats with pectins for use as food dyes.

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During Malta Polyphenols World Congress 2015, Johanna Brauch will give a talk about chemical composition and color stability of the anthocyanin-rich superfruit

Pr BrauchJohanna Brauch will give a talk during Polyphenols World Congres 2015 held in Malta on June 3-5, about maqui berries - chemical composition and color stability of the anthocyanin-rich superfruit.

"Maqui (Aristotelia chilensins (Mol.) Stuntz) is an evergreen shrub originated from South America that yields small edible purple-black berries. Due to their outstandingly high anthocyanin concentration being correlated with high antioxidant activities, the interest in the berries as a healthy coloring foodstuff or additive has significantly increased. However, the fruits were often presumed to be classified as novel food, even though their consumption in Europe is well documented since the end of the 19th century. According to these reports, berries were consumed fresh, as juice or jams, but mostly applied for coloring wine"

To know more about Malta Polyphenols World Congress 2015: www.polyphenols-site.com

Polyphenols in the News & Media

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