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Hemisynthesis of anthocyanin phase II metabolites and their characterization by LC-ESI-IMS-QTOF mass spectrometry

Sarah Schmitt Malta Polyphenols 2019Sarah Schmitt will speak about "Hemisynthesis of anthocyanin phase II metabolites and their characterization by LC-ESI-IMS-QTOF mass spectrometry" during the Malta Polyphenols 2019 Congress.

Sarah Schmitt from the University of Bonn, Germany will join the Malta Polyhenols 2019 Congress which will be held on September 30 and October 1st, 2019 in Malta.

Sarah Schmitt highlights: Until today, little is known about the biological activity of the phase II metabolites of anthocyanins. Among other reasons, especially the poor commercial availability and the high prices of the phase II metabolites pose a significant hindrance in the identification and quantification. Therefore, strategies for their synthesis are required, which may include chemical and enzymatic approaches. Novel techniques such as ion mobility mass spectrometry are promising for the analytical characterization of compounds and may serve as a basis in the search for metabolites formed in vivo”.

For more information: www.polyphenols-site.com

Phenolic compounds from wine industry by-products: characterization and in vitro bioaccesibility

Ariel Fontana Malta Polyphenols 2019 Congress

Dr. Ariel Fontana will give a presentation entitled "Phenolic compounds from wine industry by-products: characterization and in vitro bioaccesibility".

Malta Polyphenols 2019 Congress welcomes Dr. Ariel Fontana from Universidad Nacional de Cuyo (UNCUYO), Argentina.

Summary of talk: The wine industry generates a large volume of wastes, including those by-products produced before, like pruning residues (canes), and along the winemaking process such as pomaces and stems. The increase of consumers’ concerns about the use of additives in alimentary products and the attention that functional foods have attained in the last years prompted the identification of alternative sources of natural antioxidants. Several compounds present in winemaking by-products such as phenolic compounds have shown health-promoting effects and other biological properties mostly related to their antioxidant characteristics. The characterization of compounds is therefore a necessary step to increase the worth and justify their application in food industries. As well, in vitro gastrointestinal simulation is a valuable tool for investigating the effect of digestion on the phenolic compounds bio-accessibility. This approach contributes to assess the nutritional quality of a bioactive compound while encourages the development of functional foods. This talk will focus on the characterization of phenolics from winemaking by-products of Vitis vinifera L. cv. Malbec and the properties of extracts after in vitro digestion with the aim to establish their bio-accessibility

For more information: www.polyphenols-site.com

Influence of juice processing and natural variation in the bioaccessibility of phenolics from grapes and blueberries

Mario-Ferruzzi-Malta Polyphenols 2019

Prof. Mario Ferruzzi will talk about his study on Influence of juice processing and natural variation in the bioaccessibility of phenolics from grapes and blueberries.

The Organizing Committee of Malta Polyphenols 2019 Conference is honored to announce the participation of Prof. Mario Ferruzzi from North Carolina State University, USA.

Summary of Talk: The food matrix is known as a modifier of polyphenol bioavailability.  The matrix itself is influenced by genetics, agronomic conditions as well the ultimate food process chosen for production.  For example, juicing and pasteurization of purple grapes modifies both the food matrix (fractionation, structure) and polyphenol profiles (content) influencing ultimate bioaccessibility of polyphenols for uptake/metabolism by humans or the microbiota.  Additionally, while diversity in content of phenolics is commonly studied in fruit germplasm/breeding populations, variation in phenolic bioaccessibility remains largely unknown.   Exploration of natural diversity of phenolic bioaccessibility in blueberry germplasm is beginning to provide insights into matrix effects and will potentially yield genetic targets for improvement of polyphenol bioavailability from fruit products.    

 

For more information: www.polyphenols-site.com

 

 

Role of polyphenols in cognitive diseases

Yves Desjardins Malta Polyphenols 2019Prof. Yves Desjardins from Laval University, Canada will join the Malta Polyphenols 2019 Congress which will be held in Malta on September 30 to October 1, 2019 and will present his research on "Role of polyphenols in cognitive diseases".

Prof. Desjardins will speak about their recent work on polyphenols and cognitive decline in the elderly and  in the second part of the conference he will also discuss the impact of polyphenols on the gut microbiota and how it can affect the gut-brain axis.

For more information: www.polyphenols-site.com

Submit your questions and thoughts before September 6

 

Malta Polyphenols logo redTo facilitate the scientific discourse and make the conference more interactive, the scientific committee has decided to include two round table discussions that address hot topics, challenges and pressing questions related to various areas of polyphenols research.
 


Day One Round Table Discussion
Polyphenols and food applications
Chair: Prof. Andreas Schieber

  • What is the impact of established and novel processing methods on polyphenols?
  • How can we control and exploit reactions of polyphenols in food applications?
  • How can we utilize side streams of food processing more efficiently for the recovery of polyphenols?
  • Are there applications at the horizon beyond food – what about feed, cosmetics, and others?

Day Two Round Table Discussion
Polyphenols and health applications
Chair: Prof. Marvin Edeas

  • Where are we now and what are the prospects?
  • What is assured knowledge and what are the gaps?
  • How do microbiota and metabolites, the new players in the world of polyphenols, affect our classical thinking and make us rethink and redesign our strategies concerning polyphenols applications?

All participants are invited to participate in these discussions by sending their questions and thoughts before the meeting by the September 6, 2019

 

Epigenetic modulation of inflammation and synaptic plasticity by polyphenolic metabolites promotes resilience against stress in mice

Giulio Maria Pasinetti Malta Polyphenols 2019

Prof. Giulio Maria Pasinetti from Icahn School of Medicine at Mount Sinai, USA will join the Malta Polyphenols 2019 Congress and give a presentation entitlled "Epigenetic modulation of inflammation and synaptic plasticity by polyphenolic metabolites promotes resilience against stress in mice".

Summary of presentation: Major depressive disorder is associated with abnormalities in the brain and the immune system. Here, through a high-throughput screening, we identify two phytochemicals, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc) that are effective in promoting resilience against psychological stress-induced depression. We discuss the ability of DHCA/Mal-gluc to significantly reduces  depression-like phenotypes in a mouse model of increased systemic inflammation induced by transplantation of hematopoietic progenitor cells from stress-susceptible mice. DHCA reduces pro-inflammatory interleukin 6 (IL-6) generations by inhibiting DNA methylation at the CpG-rich IL-6 sequences introns 1 and 3, while Mal-gluc modulates synaptic plasticity by increasing histone acetylation of the regulatory sequences of the Rac1 gene. This study suggests that polyphenolic metabolites capable of influencing peripheral inflammation and synaptic maladaptation may eventually be implemented as novel therapeutic interventions for promotion of mental health.

For more information: www.polyphenols-site.com

Natural and bioinspired phenolic compounds as skin depigmenting agents: Recent Advances

Lucia-Panzella Malta Polyphenols 2019

The Organizing Committee of Malta Polyphenols 2019 Conference is honored to announce the participation of Dr. Lucia Panzella from the University of Naples "Federico II", Italy.

Dr. Panzella will speak about "Natural and bioinspired phenolic compounds as skin depigmenting agents: Recent Advances" during the special session dedicated to Polyphenols and Skin.

Dr. Panzella highlights: "Several skin pigmentary disorders are associated with the overproduction of melanin as the result of an abnormal function of melanocytes. One of the most common approach for control of pigmentation involves the inhibition of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis. The talk will focus on the tyrosinase inhibition properties of a series of natural and bioinspired phenolic compounds for the development of novel depigmenting agents."

During this special session, Malta Polyphenols 2019 Speakers will highlight the strategic roles of polyphenols and phenolics compounds as antioxidants (anti-UV) and anti-inflammatory agents. We will also discuss the polyphenols formulation and skin pigmentation. We will dedicate time to all innovations related to polyphenols'  use in skin care and skin aging.

 

You can submit your Abstract and innovation before July 15, 2019.

 

For more information: www.polyphenols-site.com

 

 

Polyphenols in prevention of skin photoaging and cosmetic applications

Liudmila Korkina Malta Polyphenols 2019During the Malta Polyphenols 2019, a special  session will be dedicated to Skin and Polyphenols.

Among the speakers of this special session, Prof. Liudmila G. Korkina from Moscow Centre for Innovative Biotechnological Investigations, Russia, will give a presentation entitled "Polyphenols in prevention of skin photoaging and cosmetic applications".

For more information: www.polyphenols-site.com

Use of nanosystems to improve delivery of polyphenols for skin repair

CADDEO CARLA Malta Polyphenols 2019Dr. Carla Caddeo  will give a presentation entitled "Use of nanosystems to improve delivery of polyphenols for skin repair" during the Special session dedicated to Polyphenols and Skin.

Dr. Carla Caddeo from the University of Cagliari, Italy will join the 13th World Congress on Polyphenols Applications: Malta Polyphenols 2019 which will be held in Malta on September 30 -  October 1, 2019.

Summary of presentation: The beneficial health effects of polyphenols have been extensively studied in the past years. However, their potential therapeutic and prophylactic applications are restricted by low bioavailability, poor water solubility and stability. In this framework, nanoparticulate systems are gaining increased attention as innovative delivery systems for poorly bioavailable compounds, as they ensure high stability, incorporation of hydrophilic/hydrophobic substances, high carrier capacity, and feasibility of various administration routes. Additionally, they can be designed to allow controlled release of the payload, thus enabling reduction of dosing frequency: bioefficacy is amplified and side-effects and costs are reduced, while increasing patient compliance.

 

During this special session, we will highlight the strategic roles of polyphenols and phenolics compounds as antioxidants (anti-UV) and anti-inflammatory agents. We  will  also discuss the polyphenols formulation and skin pigmentation. We will dedicate time to all innovations related to polyphenols' use in skin care and skin ageing.

You can submit your Abstract and innovation before July 15, 2019.

For more information: www.polyphenols-site.com

Dietary agents - and their microbial metabolites - as epigenetic modulators in human health & disease

Clarissa Gerhauser Malta Polyphenols 2019

Dr. Clarissa Gerhäuser from German Cancer Research Center, Germany will join the Malta Polyphenols 2019 Congress and give a presentation during a special session dedicated to Polyphenols and Microbiota.

Dr. Gerhäuser will present the research work entitled "Dietary agents - and their microbial metabolites - as epigenetic modulators in human health & disease".

Dr. Gerhäuser's main aim of research is the investigation of epigenetic alterations associated with breast and prostate cancer. A recent focus is on the “Metabolic Syndrome” and the possibility to prevent or modulate epigenetic deregulation by dietary intervention.

 

For more information: www.polyphenols-site.com

Bonn Polyphenols 2018 saw an unprecedented diversity of topics in polyphenols research

 Bonn-Polyphenols-2018-pictures-group

Bonn Polyphenols 2018 saw an unprecedented diversity of topics in polyphenols research

In continuation of 11 successful conferences, the 12th edition of the World Congress on Polyphenols Applications was held in Bonn at the end of September 2018. This two-and-a-half day event took place in the new lecture hall building of the University of Bonn, which celebrates its 200th anniversary in 2018. Local organizer Prof. Dr. Andreas Schieber, Chair of Molecular Food Technology, and his team welcomed more than 210 attendees coming from all continents and representing both the academia and the industry, who witnessed a broad range of topics unprecedented in this series of conferences. Extended lectures, numerous short oral presentations, and close to 100 poster presentations built the scientific framework of this conference and included, among others, polyphenols-microbiome interactions, metabolism and health effects, chemistry and analysis, food technology and biotechnology, plant physiology, and innovative applications of polyphenols. A special session on polyphenols as natural pigments and antioxidants was dedicated to Prof. Dr. Reinhold Carle from the University of Hohenheim, Stuttgart, for his outstanding contributions to polyphenols research. The laudatio was held by one of his former mentees, Prof. Dr. Ralf Schweiggert.

The introductory session focused on polyphenol-microbiota interactions, with extended presentations given by Prof. Dr. Marvin Edeas, Dr. Daniela Graf, and Prof. Dr. Michael Gänzle. For the first time in this series of conferences, two lectures addressed biotechnological aspects of polyphenols. Prof. Dr. Matteos Koffas provided an overview of the development of microbial platforms for plant polyphenols production, and Prof. Dr. Wilfried Schwab presented his latest findings on the biosynthesis of acylphloroglucinols in strawberries. Prof. Dr. Ute Nöthlings reviewed epidemiological perspectives of polyphenols and chronic disease risk. Prof. Dr. Jan Frederick Stevens showed that non-estrogenic derivatives of xanthohumols improve cognitive function in diet-induced obese mice. According to Dr. Sebastian Soukup, considerable species differences can be observed in isoflavone metabolism, which may have biological implications. Analytical advances in polyphenols research were presented by Dr. Christoph Steingass, who introduced unique phenolic compounds as authenticity markers of pineapple. Prof. Dr. Richard Maroun and Dr. Christine Fuchs highlighted the potential of by-products emerging from plant food processing. Prof. Dr. Mario Ferruzzi and Prof. Dr. Isabel Odriozola Serrano provided an overview of the effects of processing on the stability and bioactivity of phenolic compounds. Dr. Kirsten Berger reported on the in vitro inhibitory effects of phenolics from red fruit juices on alpha-amylases and alpha-glucosidases. Tannin-rich blends of polyphenols may be used as alternative growth promotors in poultry chicken, as demonstrated in a study presented by Dr. Leandro Martin Redondo. Prof. Dr. Reinhold Carle reviewed strategies to enhance the color stability of anthocyanins, and Dr. Judith Müller-Maatsch investigated phenolics from mango peels and rooibos as copigments.

During a live broadcast in the lecture hall building where the conference was held, the University of Bonn received notification of six successful applications for German Clusters of Excellence, and the Rector of the University of Bonn, Prof. Dr. Dr. Michael Hoch, invited the conference participants to celebrate this huge success with the University.

Prof. Dr. Mario Ferruzzi from North Carolina State University Kannapolis, USA, received the 2018 Polyphenols Award for his presentation “Effects of processing on the bioactivity of phenolic compounds”. Prof. Dr. Dea Anton from the Estonian University of Life Sciences was recognized for her poster presentation “Antimicrobial and antioxidative effects of rhubarb, tomato and berry powder in raw and cooked pork”.

In his concluding remarks, Andreas Schieber highlighted the impressive quality of the congress contributions and announced that the 13th edition of the World Congress on Polyphenols Applications will take place in 2019. The search for a venue will be a priority task of the scientific committee and the outcome will be published in due course.

During the congress, The Scientific Committee descerned following awards:

 ferruzzi-polyphenols 2018

Scientific Contribution Award

 "Processing as a modifier of polyphenol delivery and bioactivity"

Prof. Mario Ferruzzi, North Carolina State University, Kannapolis, USA
Read more

 anton-dea-award

Poster Presentation Award

Antimicrobial and antioxidative effects of rhubarb, tomato and berry powders in raw and cooked pork".

Dea Anton, Estonian University of Life Sciences, Estonia
Read more

 

 
   



 

On behalf of all the members of Scientific Committee and President, we thank you for your participation. See you next year.

Prof. Mario Ferruzzi was awarded for his scientific contribution

ferruzzi-polyphenols 2018During the 12th World Congress on Polyphenols Applications organized in Bonn, Germany on September 25-28, 2018, the Scientific Committee awarded Prof. Mario Ferruzzi from North Carolina State University, Kannapolis, USA for all his scientific achievements in the field of Polyphenols.

Prof. Mario Ferruzzi gave a strategic presentation about “Processing as a modifier of polyphenol delivery and bioactivity

Summary
"As evidence mounts for a health-protective role for dietary polyphenols, the importance of understanding factors that modify the delivery of specific polyphenol metabolites to target tissues has increased.  Food formulation and processing are believed to be significant modifiers of polyphenol bioavailability. This lecture presented data from our past and ongoing efforts focused on understanding food matrix and processing parameters as they intersect with select physiological factors to impact absorption, metabolism and tissue distribution of polyphenols.
 

The poster contribution award was delivered to Dea Anton

anton-dea-award

During the 12th World Congress on Polyphenols Applications organized in Bonn, Germany on September 25-28, 2018, the Scientific Committee awarded Dea Anton from Estonian University of Life Sciences, Estonia for her poster presentation entitled “Antimicrobial and antioxidative effects of rhubarb, tomato and berry powders in raw and cooked pork".

"Our research group participated at the congress with two poster presentations, the results of the research, carried out under the international project SUSMEATPRO and Estonian University of Life Sciences financed project.

In preliminary tests (poster presented by Piret Raudsepp) different plant parts of different cultivars with the best antioxidative and antimicrobial properties were selected for further use as berry or vegetable powders in meat products. The product studies showed the capability of plant supplements to reduce bacterial load, inhibit lipid oxidation, prolong the shelf-life and improve sensory qualities of meat products. The ongoing and future research will be focused on plant powder blends and finding out specific polyphenolic compounds responsible for these beneficial effects.

We attended the World Congress on Polyphenols Applications for the first time and we enjoyed it very much. It was a well organized event, interesting oral presentations, plenty of room for posters and time to read, think and discuss. We met the researchers of different research fields willing to co-operate and representatives of food industry interested in our results. We got good memories and experience from this year. The recognition motivates us to continue our research, to achieve more interesting results and present our findings at forthcoming congresses".

Important/Bonn Polyphenols Congress venue Exact address

Dear Attendees of Bonn Polyphenols 2018, 
 
 
We remind you the exact address of venue for the congress:
 
Endenicher Allee 19c, D-53115 Bonn, Germany
 
Please use this address instead of address marked on your Ticket.
 
 
Best regards, 
 
Bonn Polyphenols Secretariat
Updated program and Info

Prof. Ralf Schweiggert will join the Bonn Polyphenols 2018 to give a laudation

Ralf-Schweiggert

Prof. Dr. Habil. Ralf Schweiggert will join the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018 and will give a laudation to Professor Reinhold Carle to honor his considerable achievements in research on polyphenols.

Professor Dr. habil. Ralf Schweiggert holds the full professorship “Analysis and Technology of Plant-based Foods” at Geisenheim University in Germany. Prior to working several years in the nutraceutical industry at DSM Nutritional Products (Kaiseraugst, Switzerland), he has been a post-doctoral mentee of Professor Reinhold Carle at the University of Hohenheim for several years.

For more information: www.polyphenols-site.com

Biosynthesis of acylphloroglucinols: novel phenolics from strawberry fruit

Schwab Wilfried Polyphenols 2018 Prof. Wilfried Schwab from Technical University of Munich, Freising, Germany will talk about "Biosynthesis of acylphloroglucinols: novel phenolics from strawberry fruit" during the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018 which will be held at the University of Bonn, Germany in September 25-28, 2018.

Summary of talk: "Polyphenolic compounds have health-promoting properties and are a major group of secondary metabolites in fruit crops. Through reverse genetic analysis of the functions of ripening-related genes in strawberry (Fragaria × ananassa) we discovered four acylphloroglucinol (APG)-glucosides as native Fragaria spp. fruit metabolites whose levels were differently regulated in the transgenic fruits. The biosynthesis of the APG aglycones was investigated by examination of the enzymatic properties of three recombinant Fragaria vesca chalcone synthase proteins."

For more information: www.polyphenols-site.com

Impact of diet on human gut microbiota composition and functionality

Daniela Graf

Dr. Daniela Graf from Max Rubner-Institut, Karlsruhe, Germany will present on overview on the role of diet on the human gut microbiota during the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018 which will be held at the University of Bonn, Germany in September 25-28, 2018.

According to Dr. Graf:
Diet is a key factor that influences gut microbiota composition. Specific diets e.g. Western diets have an impact on gut microbiota composition and thus it’s functionality, which in turn will influence host health. The aim of this speech is to summarize how diet can affect gut microbiota composition and it will give an overview of recently published evidence from human in vivo studies on the gut microbiota-modulating effects of diet.

 

For more information: www.polyphenols-site.com

To know more about Bonn Polyphenols 2018 Speakers & Agenda, please click here

Polyphenols-microbiome interactions from a food microbiologist’s view

michael-ganzle-Polyphenols-2018

Prof. Michael Gänzle from the University of Alberta, Canada, will present on the interactions of phenolic compounds and intestinal microbiota during the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018 which will be held at the University of Bonn, Germany in September 25-28, 2018.

Phenolic compounds have multi-faceted interactions with intestinal microbiota, which are based on their use as substrate for microbial metabolism, their direct and selective antimicrobial activity, and their interference with polysaccharide hydrolysis by host and intestinal enzymes. This presentation will explore the modulation of intestinal microbiota, using microbiota of (fermented) foods as experimentally tractable models for intestinal ecosystems.

For more information: www.polyphenols-site.com

Stabilization of anthocyanins by co-pigmentation using mango peel and rooibos phenolics

Judith-Muller-MaatschDuring the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018, Judith Müller-Maatsch from University of Hohenheim, Germany will talk about "Stabilization of anthocyanins by co-pigmentation using mango peel and rooibos phenolics".

Short summary of talk: "Anthocyanins are highly susceptible to light exposure, temperature, and oxygen, thus, the color of anthocyanin-rich products lacks in stability during processing and subsequent storage. Anthocyanins’ susceptibility to degradation is primarily determined by their molecular structure and the surrounding matrix, i.e. pH, water activity, hydrocolloid content, and concomitant phenolic compounds named co-pigments. Co-pigmentation describes the interaction of anthocyanins and co-pigments that results in a modulation of color and a change in anthocyanin stability. Phenolics of mango peels as well as rooibos have been observed to effectively modulate the color of strawberry anthocyanins. Whereas phenolics based on gallic acid deriving from mango peel  pronouncedly modulated the color, phenolics from rooibos further increased the stability of anthocyanins during heating."

For more information: www.polyphenols-site.com

Investigating the biological activities of extracts from winery by-products

Christine Fuchs Bonn Polyphenols 2018

During the 12th World Congress on Polyphenols Applications: Bonn Polyphenols 2018, Christine fuchs, from Technische Universitaet Kaiserslautern, Kaiserslautern, Germany will talk about "Investigating the biological activities of extracts from winery by-products".

Talk summary: Winery by-products, such as pomace, stem, grapevine leaves and shoots, arise in high amounts during the wine-making process. Due to high contents of secondary plant metabolites, such as polyphenols, their usage as sources of bioactive compounds offers an opportunity to obtain value-added products from these by-products for the food, cosmetics and pharmaceutical industry. The aim of the present study was to investigate extracts from winery by-products of vitis vinifera L. cv. Riesling concerning their chemical composition and biological activities in vitro. Effects on cell viability, intracellular ATP, the mitochondrial membrane potential (MMP) and intracellular ROS were determined in the human hepatocarcinoma cell line HepG2.

For more information: www.polyphenols-site.com

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