News Alert
Sustainable sources for Polyphenols Recovery and their Application in Healthy Food
Dr. Isabella D’Antuono from the Institute of Sciences of Food Production National Research Council (ISPA – CNR), Italy, will join the Polyphenols Applications 2023 Congress and present the talk entitled "Sustainable Sources for Polyphenols Recovery and their Application in Healthy Food".
Functional foods are an innovative response of food industries to consumer expectations. Their sector includes foods naturally rich in bioactive compounds or enriched in bio-ingredients stemming from unexploited sources, as a virtuous application of the circular economy concept.
Join us in Polyphenols Applications 2023 to learn more about Dr. D’Antuono's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Polyphenols in Depression & Neurodegenerative Diseases
Prof. Giulio Maria Pasinetti from 
Icahn School of Medicine at Mount Sinai, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Polyphenols in Depression & Neurodegenerative Diseases".
Join us in Polyphenols Applications 2023 to learn more about Dr. Pasinetti's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Book your hotel and benefit from the best rate
Corinthia Palace Malta will be the conference hotel of Polyphenols Applications 2023 on September 28-29.
Hotel Booking for Attendees: Special Rate
This year's attendees will be able to benefit from a discount on their booking at the conference hotel.
Available rooms include: Deluxe double, executive double, and executive suites for sole use.
The room rate includes full breakfast and VAT. Please note that the offer is valid until July 31, with a limited number of rooms.
Book you room with a preferential rate now.
If you need more than 2 rooms, please contact the hotel directly via email, mentioning that you will attend Polyphenols Applications 2023.
More about the hotel and activities in Malta.
Registration Details
Register early and book your spot to to learn about this year's new scientific outlook on Polyphenols Applications in lovely Malta.
Polyphenols Applications Congress
September 28-29, 2023 - Malta
Plant-Derived Polyphenols as Senolytic Agents
Cellular senescence is a basic aging process that drives several age-related degenerative conditions. Compounds that selectively eliminate senescent cells, commonly called “senolytics”, have the potential to improve multiple degenerative conditions by targeting this key age-promoting process.
Several polyphenols have been shown to have senolytic activity, including the hops-derived chalconoid xanthohumol, presenting a new pathway by which these molecules might improve degenerative disease.
Dr. Christopher Wiley from Tufts University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Plant-Derived Polyphenols as Senolytic Agents".
About Dr. Wiley
Dr. Wiley is a Scientist II at the Jean Mayer USDA Human Nutrition Research Center on Aging and an Assistant Professor in the School of Medicine at Tufts University. His laboratory studies the interactions between metabolism and cell fate decisions such as cellular senescence and cell death, primarily in the context of aging and degenerative disease.
Join us in Polyphenols Applications 2023 to learn more about Dr. Wiley's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Cranberry Polyphenols Inhibit Esophageal Cancer Through Reshapeing the Microbiome-Metabolome Axis
Dr. Laura Kresty from the University of Michigan, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Cranberry Polyphenols Inhibit Esophageal Cancer Through Reshapeing the Microbiome-Metabolome Axis".
Join us in Polyphenols Applications 2023 to learn more about Dr. Kresty's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Catechol-based Nanostructures in Medicine
Prof. Daniel Ruiz Molina from Universitat Autònoma de Barcelona, Spain, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Catechol-based Nanostructures in Medicine".
The experience and background of the team brings an important asset in the synthesis of “sticky” catechol based coatings and nanoparticles with bioadhesion properties in humid conditions. This involves: I) Synthesis of nanoparticles/nanocapsules intended for chemo-/phototherapy with encapsulated drugs and study of the controlled release, II) novel coating for biofunctionalization, colloidal stabilization in physiological media experimental conditions and III) a patch to damaged tissue that allow for the growth of healthy cells in a very effective way that will naturally induce a faster regeneration of the tissue.
Join us in Polyphenols Applications 2023 to learn more about Prof. Ruiz's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols
Dr. Diana Roopchand from Rutgers University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Multi-omics Approach Reveal Biomarkers of Metabolic Resilience in Healthy Participants Supplemented With Grape Polyphenols".
Grape polyphenols (GPs) extracted from grape pomace are rich in proanthocyanidins (PACs) compounds which are not bioavailable; however, evidence suggests their health benefits are likely mediated via the gut microbiota and/or bacterial metabolites.
Serum, fecal, and/or urine samples were collected before and after 2, 4, and 10 days of GP supplementation followed by shotgun metagenomic sequencing, mass spectrometry-based metaproteomics, and/or targeted metabolomics. Notable GP-induced bile acid changes appeared to be gender-specific and correlational analyses uncovered novel associations between gut microbes and metabolites associated with metabolic resilience.
Join us in Polyphenols Applications 2023 to learn more about Prof. Roopchand's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Phenolic Compounds, Bioaccessibility and Characterization in Foods
Prof. Trust Beta from the University of Manitoba, Canada, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Phenolic Compounds: Their Characterization and Bioaccessibility in Cereal Foods".
Globally, cereal grains serve as a source of affordable, staple foods. They comprise minor phytochemicals which may function to reduce oxidative stress. Grain phenolics are among compounds of interest as they have been shown to exhibit antioxidant and anti-inflammatory functions. Their characterization and bioaccessibility in cereal grains will be discussed during this presentation.
Join us in Polyphenols Applications 2023 to learn more about Prof. Beta's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Biological Activities of Phenol-Amino Acid Adducts: Towards enhancing Food Quality
Dr. Marianne Nissen Lund from the University of Copenhagen, Denmark will join the Polyphenols Applications 2023 congress and give a major presentation entitled "Biological Activities of Phenol-Amino Acid Adducts: Towards Enhancing Food Quality".
When polyphenols are oxidized to quinones they react with proteins in foods, with cysteine residues on proteins being kinetically preferred targets. Caffeic acid-cysteine and chlorogenic acid-cysteine adducts have been detected in commercial coffee-milk drinks. Thus, these adducts were synthesized and their anti-inflammatory activity was tested in lipopolysaccharide-treated RAW 264.7 cells in comparison to their parent phenolic acids.
Dr. Lund's results demonstrate that the addition of a cysteine moiety to phenolic acids enhances their anti-inflammatory responses in macrophages.
Join us in Polyphenols Applications 2023 to learn more about Dr. Lund's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
The Latest Advances in the Biotechnological Production of Phenolic Compounds
Dr. Matheos Koffas from the Rensselaer Polytechnic Institute, School of Engineering, USA will join the Polyphenols Applications 2023 congress and will give a major presentation entitled "The Latest Advances in the Biotechnological Production of Phenolic Compounds".
Join us in Polyphenols Applications 2023 to learn more about Dr. Koffas's talk during the session "Polyphenols & Food Research: The Most Recent Developments".
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Dietary Polyphenols Inhibit Production of Trimethylamine, a Gut Microbial Metabolite Associated With Aging and Atherosclerosis
Prof. Andrew P. Neilson, North Carolina State University, USA, will join the Polyphenols Applications 2023 congress and will present a talk entitled "Dietary Polyphenols Inhibit Production of Trimethylamine, a Gut Microbial Metabolite Associated With Aging and Atherosclerosis".
Cardiovascular disease causes ~32% of deaths worldwide. Elevated blood trimethylamine N-oxide (TMAO) levels were identified in 2011 as a risk factor for atherosclerosis development. TMAO is formed through a microbial-host axis involving oxidation of dietary choline to trimethylamine (TMA) by gut bacteria containing the cutC/D gene cluster. TMA is absorbed into circulation and oxidized to TMAO by hepatic flavin-containing monooxygenase 3. TMAO promotes cardiovascular disease through multiple mechanisms.
There is no FDA-approved drug to control TMAO levels, underscoring the need for complementary strategies to manage TMAO production. Dietary phytochemicals such as phenolics represent one potential solution. Phenolics have shown promise for altering the structure and function of the gut microbiome and providing cardioprotective benefits. Interest is emerging in TMAO-lowering activities of phenolics. There is a need to rapidly screen large numbers of phenolics and other dietary bioactives (compounds foods, extracts, etc.) to identify potential lead compounds for subsequent preclinical animal studies.
Prof. Neilson and his team developed and validated a high-throughput, low-volume 96-well ex vivo-in vitro anaerobic fecal fermentation method using human fecal samples and choline-d9 substrate and measuring the resultant TMA-d9. They paired this with a rapid, high-throughput analytical platform by employing an automated liquid handling robot for sample prep and a fast, sensitive 96-well LC-MS/MS method. Model validation experiments confirmed that choline-d9 utilization and TMA-d9 production occur with ~1:1 stoichiometry, with no background interference, and are dependent upon the presence of gut bacteria. Using this model, they identified chlorogenic acid, epicatechin and foods rich in these phenolics (coffee, cocoa and artichoke) as potent TMA production inhibitors.
In vitro and animal studies will elucidate the mechanisms of inhibition and demonstrate efficacy in vivo. TMA/TMAO-lowering activities may be a previously unknown mechanism by which dietary phenolics exert their cardioprotective effects.
Join us in Polyphenols Applications 2023 to learn more about Prof. Neilson's talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Berries Polyphenols & Vascular Function: Current Evidence and Mechanisms of Action
Prof. Cristian Del Bo', from the Università degli Studi di Milano, Italy, will join the 16th World Congress on Polyphenols Applications 2023 and give a talk entitled "Berries Polyphenols & Vascular Function: Current Evidence and Mechanisms of Action".
Join us in Polyphenols Applications 2023 to learn more about Prof. Del Bo''s talk.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Hormetic response to B-type procyanidin ingestion may involve stress-related neuromodulation via the gut–brain axis: Preclinical and clinical observations
Dr. Naomi Okasabe, from Shibaura Institute of Technology, Japan will join the Polyphenols Applications 2023 congress which will be held in Malta, on September 28-29, 2023, and present the "Hormetic response to B-type procyanidin ingestion may involve stress-related neuromodulation via the gut–brain axis: Preclinical and clinical observations".
B-type procyanidins, a series of catechin oligomers, reduce cardiovascular disease risk and impact central nervous system (CNS) function. Comprehensive analyses of previous reports indicate an optimal mid-range dose for the hemodynamic effects of B-type procyanidins, with null responses at lower or higher doses, suggesting hormesis. Dr. Okasabe previously confirmed the hormesis of hemodynamic responses to B-type procyanidins in animal studies, in addition, our work has linked these effects to the CNS. In this presentation, we evaluate the hormetic response elicited by B-type procyanidins, recontextualizing the results of intervention trials. In addition, Dr. Okasabe will discuss the possibility that this hormetic response to B-type procyanidins arises via CNS neurotransmitter receptors.
Join us in Polyphenols Applications 2023 and benefit from the experience of professional researchers like Dr. Okasabe.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Marine Polyphenols - Characterization and Applications
Prof. Monica Jordheim, University of Bergen, Norway will join the Polyphenols Applications 2023 congress to present a talk on "Marine Polyphenols - Characterization and Applications".
The world's population is projected to reach 9 billion by 2050, and utilization of bioresources will be increasingly important for food, feed, and health applications. Seaweeds, or macroalgae, are a sustainable biomass and they play an increasing role in aquaculture and marine bioresource development. However, they are still identified as an underexplored resource – and marine polyphenols are less explored compared to terrestrial polyphenols.
Prof. Jordheim will, in this presentation, discuss the importance of quantification and identification at the molecular level in order to uncover and understand the algae's potential in industrial applications. The experienced challenges in working with seaweed biomass compared to terrestrial biomass will be addressed, and results from industrial projects will be presented.
About Prof. Jordheim
Prof. Jordheim has over twenty years of experience in quantification and identification of polyphenols, including full molecular elucidation using NMR and HR-LC-MS. She has co-authored several book chapters on the chemistry of anthocyanins and identified more than twenty new structures from nature. The recent years Jordheim has focused on polyphenols from seagrasses and seaweeds including industrial collaborations and innovation projects. Prof. Jordheim is also the head of education at the Department of Chemistry at University of Bergen, Norway, and the leader of the larger research group Bioresources and Pharmaceutical Chemistry (BPC).
Join us in Polyphenols Applications 2023 and benefit from the experience of professional researchers like Prof. Jordheim.
Polyphenols Applications 2023 Congress
September 28-29, 2023 - Malta
www.polyphenols-site.com
Corinthia Palace Malta will host Polyphenols Applications 2023 Congress
The 16th World Congress on Polyphenols Applications 2023 will be held on September 28-29 at
*****
Corinthia Malta Palace is one of the best luxury hotels in Malta. The hotel benefits from an ideal location from which to explore Malta. The walled city of Mdina is only 4 km away and the popular resort town of St. Julian's is 7 km away. You will be staying opposite the Presidential Palace, next to the magnificent Saint-Antoine Botanical Garden. Set in beautifully landscaped gardens, Corinthia Palace Malta offers a peaceful setting for a relaxing stay.
Book your room with a special rate
The committee of Polyphenols Applications offers all attendees a special reduced rate for all rooms booked at Corinthia Hotel, including VAT and breakfast.
Please note that the offer is valid until August 31, with a limited number of rooms.
Book your room with a negotiated price.
If you need more than 2 rooms, please contact the hotel directly via email, mentioning that you will attend Polyphenols Applications 2023.
Airport
Malta International Airport is located between the villages of Luqa and Gudja, 10kms from Valletta.
Passports & Visas
For information about Visa applications, please visit the website of the Maltese Ministry for Foreign Affairs.
Transports in Malta
To have a better view on the different kind of transports you can use in Malta, please click here.
More about Malta
In Malta, you'll explore 7000 years of history yet live passionately in the present. You'll span the millennia with an astonishing array of things to discover. And wherever you go, the Islands' scenery and architecture provide a spectacular backdrop. The colours are striking, honey-coloured stone against the deepest of Mediterranean blues.
The Maltese Islands have been described as one big open-air museum. What makes them unique is that so much of their past is visible today. Delve into the Islands' mysterious prehistory, retrace the footsteps of St. Paul or see where the Knights of St. John defended Christendom.
In just 48 hours and a kilometre or two, you can try a new sport, laze on an island cruise and tour the most important historic sites, and still have time to join in the nightlife. That’s the real advantage of a stay here.
The Islands offer plenty of specialist holidays for those seeking to learn a new skill, discover history or get fit. If you’re interested in sports, we cater as much for the seasoned enthusiast as the casual first-timer. Malta has wellness and spa facilities at the luxury hotels and club resorts. Sea and land lend themselves to activities from rock-climbing to gentle rambling.
For a tempo and scene change from Malta itself, hop to the sister islands of Gozo and Comino. Here, you'll holiday within a holiday and at the most relaxed of Mediterranean paces.
Share Your Abstract During Polyphenols Applications 2023
The abstract submission process for Polyphenols World Congress 2023 is now open.
Get your abstracts ready and share them with the scientific committee to communicate your work with worldwide scientists, industrials, and polyphenols enthusiasts.
Abstracts related to the following topics can be submitted. Submit an abstract.
Feel free to contact us for any questions.
Media Contact:
Polyphenols Applications Team
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Polyphenols Applications Conference
September 27-29, 2023
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Photographed Souvenirs of Polyphenols Applications 2022
Thank you for sharing us memories of Polyphenols Applications 2022. You can now view this year's photographed moments.
Prof. Juan Carlos Espin was discerned the Scientific Award 2022
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The scientific committee of Polyphenols Applications 2022 awarded Prof. Juan Carlos Espín, Spanish National Research Council, Spain, the Best Scientific Award of the year during the 15th #PolyphenolsWorldCongress. This award was given for his brilliant presentation about the past, present, and future research on polyphenols "Polyphenols 2022: Where We Are Now and What’s Next". Prof. Espín gave an exhaustive presentation about the current research on polyphenols, as well as clear vision on the future of polyphenol research, raising many questions that can be useful in furture research:
Prof. Espín stated: “I am very grateful to the Scientific Committee of the Polyphenols Applications Congress 2022 for this recognition. The Best Scientific Contribution Award is undoubtedly a great honor. I am proud to have spread the importance of polyphenol research through this renowned forum.” The scientific committee congratulates Prof. Juan Carlos Espín for his achievement and is looking forward to learning more about his studies. |
Extract of Prof. Juan Carlos Espín's presentation
You can watch his interesting presentation if you missed it by ordering the conference's replay. Know more about it.
Polyphenols Applications 2022 Congress
September 28-30, 2022 - Valencia, Spain
#PolyphenolsWorldCongress
www.polyphenols-site.com
The committee awarded 3 Poster Presentations during Polyphenols Applications 2022
During the 15th #PolyphenolsWorldCongress which was held on September 28-30 2022 in Valenci, the committee chose 3 Best Poster Presentations which were distinguished by their quality of research and presentation.
Klara Supikova, Palacky University Olomouc, Czech Republic was discerened an award for her poster entitled "Sulfated Phenolic Acids are Common Plant Metabolites".
This study describes mainly novel sulfated derivatives of phenolic acids identified in plants. Only some of these compounds were detected before, nevertheless, only in marine species (seagrasses and algae).
Klara stated: "In the future, I would like to focus on the identification of other unknown potentially sulfated compounds present in nature, as we already know, the plant "sulfatome" is quite rich in some cases. A challenging task for me and my colleagues will be the discovery of sulfotransferases responsible for the biosynthesis. Moreover, the definition of the physiological functions of sulfated phenolics in plants remains also unclear, thus, I would like to direct my research activities to answer these questions."
Another poster award was given to Sandra Mariño-Cortegoso, University of Santiago de Compostela, Spain, for her contribution "Recovery of Bioactive Compounds From Lime and Lemon By-Products Through Sustainable Methodologies".
When asked, Sandra affirmed: “This work is a part of the research project VALICET focuses on the valorization of fruit by-products using green extraction technologies for future approaches in the application of fruit by-products as food ingredients and additives through the recovery of added-value compounds. Future work will be done on the encapsulation of the bioactive compounds to develop ingredients, edible and active packaging and coatings to extend food shelf-life."
Katia Ruel, ADKALIS - Groupe BERKEM, France, was also discerned an award for her poster contribution "Plant Polyphenolic Extract From Berkem Biosolutions® for Antimicrobial Protection of Cosmetic Products".
Katia stated: "In keeping with my interest in the activity of polyphenols in the domains of cosmetics and of protection of wood and grains against biological predators, my research in collaboration with Groupe Berkem R&D laboratories will deepen understanding of the mechanisms underlying the action of these natural plant polyphenolics extracts.”
The scientific committee of Polyphenols Applications congratulates the winners once again. We will be looking forward to learning about their progress during the next edition.
If you missed on the posters, you can access all absracts by ordering the abstracts book.
Polyphenols Applications 2022 Congress
September 28-30, 2022 - Valencia, Spain
#PolyphenolsWorldCongress
www.polyphenols-site.com
3 Short Oral Presentation Awards were given in 2022
Many Short Oral Presentations were submitted during the 15th #PolyphenolsWorldCongress, held on September 28-30 2022 in Valencia, Spain. The committee voted for the best 3 of these short oral presentations.
Paul Besrukow, Geisenheim University, Germany, was awarded the first prize of the Best Short Oral Presentation 2022 for his studies on "Grape Cane Stilbenoids as Biopesticides in Organic Viticulture".
Mr. Besrukow is working on the analysis, valorization and application of polyphenols extracted from agricultural by-products. In scope of the joint project VITIFIT, which focuses on the reduction of copper usage in organic viticulture, he investigates the antifungal efficacy of differently formulated stilbenoid-rich grape cane extracts on Plasmopara viticola, causal agent of grapevine downy mildew.
Cornelia Schmutz, University of Vienna, Austria, received the second best short oral presentation award for her contribution on "Anthocyanin-Rich Berry Extracts and Chemotherapy: A Critical Combination".
Irinotecan, as pro-drug of SN-38, is a frequently chosen chemotherapy option for colorectal cancer. Bioactive plant ingredients, so-called anthocyanins, are promising candidates to possibly alleviate adverse effects induced by the topoisomerase (TOPO) poison SN-38. Hence, the FWF funded project is centered on potential protective or adverse effects of anthocyanin-rich berry extracts during chemotherapy. In vitro experiments already showed reduced DNA/TOPO I intermediates, in both tumorigenic and non-tumorigenic colon cells.
Future work will focus on the relevance of the observed effects inin vivomodels of tumor-bearing animals.
The last Best Short Oral award was discerned to Learnmore Kambizi, Cape Peninsula University of Technology, South Africa, for his short oral contribution "Pigmented Potatoes: A Potential Panacea for Food and Nutrition Security and Health?"
Prof. Kambizi is a full professor of Botany at the Cape Peninsula University of Technology, South Africa. His main interests are Ethnobotany, Phytomedicine, Botany, Medicinal Plants, Sustainable utilization and conservation, Food and Nutrition Security.
His interests in working with Traditional Medical Practitioners are a major part of his work. Prof Kambizi was appointed the first Director of African Centre for Herbal Research based in Nigeria, a position he holds to date. Although Prof Kambizi is well vested in medicinal plants, he has interests in food and nutrition security with the vision 2030 UN Sustainable Development Goals in mind. These interests have led him to start work on indigenous underutilised pigmented potato cultivars. This is because of their immense potential in ameliorating food and nutrition insecurity as shown in this review that he put together. So far, he has worked on the role of root zone temperature on physiological growth and phytochemical constituents as well as biological activity, in Salad Blue, Pink Fir Apple and Highland Burgundy Red pigmented potato cultivars, among other studies. Although phytochemical constituent results look promising, the biological activities are not conclusive. Therefore, further studies are required to elucidate these activities.
Prof Kambizi stated: "Going forwards, I am interested in studying more cultivars from different parts of the world to see their responses to different biotic and abiotic stresses especially in South Africa where I am based, isolation of the main phenolic compounds, elucidation of their activities, and bioavailability of these compounds especially after processing. Bioavailability studies post processing will potentially open insights into the quality and quantity of the compounds that would be useful in human physiology and therefore link these compounds to the health benefits of these potatoes. I am actively looking for funding and collaborators to pursue these studies and I am open to any such around the globe."
If you wish to catch up on the presentations you missed, including these winning contributions, you can order the conference's replay or the abstracts book. Know more about it.
Polyphenols Applications 2022 Congress
September 28-30, 2022 - Valencia, Spain
#PolyphenolsWorldCongress
www.polyphenols-site.com
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